Cancer blood test that finds 8 kinds of tumours sounds 'promising'

A Cheap and Easy Blood Test Could Catch Cancer Early

This blood test, called CancerSEEK, could cost less than $500, which is comparable to or lower than other screening tests, such as a colonoscopy, according to the study.

Researchers at Johns Hopkins University in the U.S. announced they had developed the single blood test which can screen for the multiple forms of cancer.

Genetic mutations drive the growth of cancer cells, and dying cells shed some of this mutated DNA into the blood.

Though the technology behind the test took years to refine, the basic concept is simple and bears some similarities to other blood-based cancer detection tests like the prostate specific antigen test, which is sometimes used to screen for prostate cancer. And the test, which was developed using samples from diagnosed cancer patients, will need to be validated "in a more real-world setting, where we will be screening healthy individuals", Joshua Cohen told BioWorld. Another issue with liquid biopsies is the ability to identify the underlying tissue of origin.

Except for identifying blood malignancies, nonetheless, those tests "by and large can't completely tell whether you have tumor or some different noncancerous condition", as indicated by Mayo Clinic's site. The team at John Hopkins initially studied several hundred genes and 40 protein markers, whittling the number down to segments of 16 genes and eight proteins.

Dr. Richard Schilsky, chief medical officer of the oncology society, said results are encouraging, but the test needs more study, especially to see if it gives too many false alarms.

More news: US Withholds $65 Million From UN's Palestinian Refugee Agency, Calls for Changes

-Ph.D. student at the Johns Hopkins University School of Medicine and the paper's first author. The Nanny star Fran Drescher, who was diagnosed with uterine cancer in 2000, started her own cancer foundation that focuses on detecting cancer early on.

The scientists optimized the panel by working to the concept of diminishing returns. The main aim of the blood test is to detect signs of cancer in those people who have not been previously diagnosed with cancer previously. The result was a "small but robust" panel of highly selective DNA markers. But that will bring up questions raised by other screening tests. Last year, Purdue scientists revealed a promising study focusing on a series of proteins that could effectively signpost the presence of cancer.

The test was best at finding ovarian cancer, which it detected up to 98 percent of the time. Using the test on 812 healthy controls, Cancer SEEK produced only seven false-positive results.

One of the most important attributes of a screening test is the ability to detect cancers at relatively early stages, the author point out.

The next steps for the Johns Hopkins research team include ensuring that the test works in patients who are not symptomatic. The sensitivity was 69% or higher for ovarian, liver, stomach, pancreatic, and esophageal cancers-all types that are hard to detect early.

It also narrowed down the form of cancer, which previously published pan-cancer blood tests have not. "Will this eventually impact patients' care?"

Related News:

  • Man United's Carrick to retire at season's end - Mourinho

    Man United's Carrick to retire at season's end - Mourinho

    Jose Mourinho will be remaining at Manchester United - and will be handed an impressive transfer kitty as he does so. I think you can probably expect that in the summer. "He could be a very important player for us".
    Senator Cory Booker goes viral after speaking against Trump's sh*thole comment

    Senator Cory Booker goes viral after speaking against Trump's sh*thole comment

    What is the worst thing that allows bigotry and hate to proliferate is people who... stand by and do nothing when it's said. You know what the President of the United States is saying, especially in heated exchanges, ' he said.
    Accused cop killer now on trial

    Accused cop killer now on trial

    Barbour and Dawson then renewed their efforts, asking the judge if they could enter a plea of not guilty by reason of insanity. The suspect, Luis Enrique Monroy Bracamontes, who immigrated to the U.S. illegally, appeared in court heavily shackled.
  • Higbie Resigns from Trump Administration after Bigoted Comments Surface

    Higbie Resigns from Trump Administration after Bigoted Comments Surface

    Trump has denied he is a racist, telling a reporter on Sunday: "I'm the least racist person you have ever interviewed ". Higbie , a staunch Trump supporter, made the comments as host of the internet radio program " Sound of Freedom ".
    Office of profit case: AAP to hold emergency meeting on prevailing situation

    Office of profit case: AAP to hold emergency meeting on prevailing situation

    Arvind's tenure as the Chief Minister of Delhi has been tumultuous ever since he won the elections with majority three years ago. The BJP was quick to question if the AAP government had any "moral right" left after the EC's recommendation to the president.
    Eat Timbits, not Tide Pods: Officials warn against 'Tide Pod Challenge'

    Eat Timbits, not Tide Pods: Officials warn against 'Tide Pod Challenge'

    Besides the potential for dehydration, Noble said consumption of laundry pods could result in burns to the mouth, throat and stomach.
  • Pence heads to Middle East

    Pence heads to Middle East

    Vice President Mike Pence is greeting U.S. soldiers at Shannon Airport in Ireland hours after the federal government shutdown. The PA said it would not meet with any USA officials regarding the peace process following Trump's declaration on Jerusalem.
    Kim Kardashian and Kanye West reveal new daughter's name

    Kim Kardashian and Kanye West reveal new daughter's name

    We're betting you probably didn't see this one coming. "We are so excited to finally welcome home our baby girl", Kim wrote. Jess is a curly-haired Jersey girl who adores penguins and watches the worst reality shows on TV.

    How major U.S. stock indexes fared on Wednesday

    Hong Kong's Hang Seng added 0.4 percent after China reported 6.9 percent economic growth in 2017, faster than expected. Juno Therapeutics soared 50 percent after the Wall Street Journal reported that biotech drugmaker Celgene might buy it.
  • California community rallies behind 13 victims in 'house of horrors' case

    California community rallies behind 13 victims in 'house of horrors' case

    An aunt of the children that were found chained up recently told reporters that she was not allowed to visit them. And she said, 'I feel so very fortunate with the experiences I've had in life as I see this unfolding before me'.
    No motive uncovered in Las Vegas mass shooting

    No motive uncovered in Las Vegas mass shooting

    She said he had begun to buy firearms over the course of the a year ago and that Danley believed it was a "hobby" of his. Several bullets hit aviation fuel storage tanks at nearby McCarran International Airport, but the tanks did not explode.
    Europe storm: Germany in big clean-up as trains run once more

    Europe storm: Germany in big clean-up as trains run once more

    In Germany's eastern state of Brandenburg, police said a gust of wind flipped a truck over a highway, killing the driver. A truck and a damaged vehicle after the strong winds of the western storm in Kampen, Netherlands, on Thursday.

Most liked

Former Patriot Named Titans Head Coach
Another backup - defensive tackle Shamar Stephen - was held out for the second consecutive day with knee and ankle injuries. While previous head coach Mike Mularkey was a great leader, he often struggled with the latter half of that description.

Nintendo to launch DIY cardboard toys for the Switch
That being said, once you see how much each Nintendo Labo kit costs, you may think twice about ever throwing a creation away. It will even be possible, according to Nintendo , to invent new ways in which to play with the Toy-Cons you build.

Kidnapped Americans, Canadians Rescued in Nigeria, Police Say
The foreigners had visited Kafanchan and Kaura in Kaduna state and were heading back to Abuja at the time of the ambush. The four foreigners were rescued in the Jere area of the Kagarko local government area of Kaduna state , he said.

Macron: UK Must Pay into EU Budget After Brexit to Access Markets
French President #emmanuel macron is expected to announce the decision on Thursday as part of his visit to the UK. The juxtaposition shows how little leverage May has - and how much she needs Macron to soften his line on Brexit.

Day 6 Snapshot from the Australian Open
The wait for a home women's champion will extend into a 41st year after Barty went down 6-4 6-2 to the unseeded Osaka. However, the American was at the centre of a scary incident during the third set of the match on Rod Laver Arena .

Kodak Black Arrested On Multiple Charges In Florida
Black's Florida arrest is on top of separate charges he faces in SC , where he was indicted on sexual assault charges in October. Monday, Kodak released a video for his "Roll In Peace" single with rapper Jahseh Onfroy, better known as XXXTentacion .

Ed Sheeran engaged to high school crush
In March, he shared the details of their dreamy love story with People , revealing, "I've known Cherry since I was 11". The pair attended Thomas Mills High School in Framlingham, and have been dating for around two-and-a-half-years.

Very First 2019 Ford Mustang Bullitt Heads To Auction Today
Ford also released a teaser video for the GT500 that doesn't show the full vehicle , but does show it spitting flames. The muscle auto was donated by Ford and the McQueen estate, and all proceeds of the sale will benefit Boys Republic.

Robby Anderson arrested in Florida
He was charged with resisting an officer with violence after outside the Rolling Loud Music Festival in May. He's scheduled to appear in court for a trail hearing on March 19, according to court records.

Justice Department Wants to Re-Try Mendendez
Bob Menendez , D-N.J., after a jury deadlock resulted in a mistrial on corruption charges in November. On Friday the senator's office issued a statement batting away the case against Menendez as baseless.

IMessage Contains A Bug That Can Freeze iOS Devices
Once the victim clicks on the malicious link , the app gets bombarded by an overload of coding, causing it to crash indefinitely. He said he'd reported the bug to Apple the previous day, he told BuzzFeed , but had not heard anything from the company.

United States marshal killed, two police officers injured in Harrisburg shooting
A USA marshal was killed, while a Harrisburg police officer and York City police officer were both wounded, per KOMO News. The suspect has not been identified, but confirmed he was critically injured.

Facebook Widens Probe Into Alleged Russian Interference in Brexit
Facebook has launched an investigation into claims Russian Federation used the social network to influence the Brexit referendum .

Intel Says 90% Of Chips Affected By Spectre And Meltdown Exploits Patched
Shenoy said that the company has issued patches for 90 percent of its chips made in the previous five years but it needs to do more in that space.

Democrat wins special election for state Senate seat in Wisconsin
A turning point in politics is happening right before our eyes and it may just result in the change we've been hoping for. Once Schachtner is sworn in, Republicans will hold an 18-14 majority in the state Senate with one vacant seat.